Overview
Stem cell therapy is the therapeutic use of undifferentiated cells, capable of self-renewal and differentiation into specialized cell types, to repair, replace, or regenerate damaged or diseased tissue. It draws on embryonic, induced pluripotent, and adult stem cells, including mesenchymal stromal cells, and exploits their capacity for differentiation, paracrine signaling, and immunomodulation. Applications span regenerative medicine, tissue engineering, and disease modeling, with delivery often supported by biomaterial scaffolds that guide cell survival and integration. The peer-reviewed research collected here reflects these themes through studies of emerging regenerative-medicine paradigms in stem cell therapies, biocompatible scaffolds for induced pluripotent stem cell transplantation and modeling post-stroke recovery in three-dimensional neural culture, and human umbilical cord-derived mesenchymal stem cells as a source of odontoblasts under good-manufacturing-practice conditions. Further contributions examine cell therapy as an adjunct approach in COVID-19 sequelae, the therapeutic potential of adipose-derived mesenchymal stem cells in premature ovarian insufficiency and ovarian aging, and the ethics of modern stem cell research and therapy. Work on in vitro disease models and cardiotoxicity testing situates stem-cell-derived systems within preclinical safety evaluation. Methodologically, the literature draws on cell culture, scaffold engineering, animal and in vitro models, and bioethical analysis, illustrating how stem cell therapy connects developmental biology, biomaterials, and translational medicine in the repair and regeneration of tissue.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Biocompatible Scaffolds for Human-Induced Pluripotent Stem Cell Transplantation and Modeling Post-Stroke Recovery in Three-Dimensional Neural Cell Culture
Human Umbilical Cord-Derived Mesenchymal Stem Cells as a Source of Odontoblasts: a GMP-compliant Approach
Ethics of Modern Stem Cell Research and Therapy: Current Critical and Interdisciplinary Perspectives
Cell Therapy as an Alternative approach for COVID-19 Infection Consequences: A Non-Systematic Review
The Evolution of Fetal Surgery
Therapeutic Potential of Autologous Adipose Derived Mesenchymal Stem Cells in Human POI and Ovarian Aging
Evaluating Circadian Oscillators in Cancer Stem Cells
Expression of Estrogen Receptor β in Hypothalamic Stem Cells
MicroRNA-1285 Might Potentially Regulate OCT4 Gene Expression by Direct Targeting of its Promoter
Dual Effects of Neuroprotection and Neurotoxicity by General Anesthetics on Neural Stem Cells: Role of Autophagy
A Role for in Vitro Disease Models in the Landscape of Preclinical Cardiotoxicity and Safety Testing
How this research is being cited
The 12 articles above have been cited 11 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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Zahirrah Begam Mohamed Rasheed et al. · 2023 · Biology
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2023 · Biology
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Luján Irastorza Jesús Estuardo et al. · 2022 · Obstetrics & Gynecology International Journal
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2022 · Obstetrics & Gynecology International Journal
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2021 · Stem Cell Reviews and Reports
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2021 · Stem Cell Reviews and Reports
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2017 · Journal of Evolving Stem Cell Research
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A role for in vitro disease models in the landscape of preclinical cardiotoxicity and safety testing2017 · Journal of Evolving Stem Cell Research
A sample of recent works citing this journal's research on Stem Cell Therapy, linking to each citing work.