Overview
Stem cell research is the scientific investigation of undifferentiated cells that possess the capacity for self-renewal and differentiation into specialized cell types, aiming to understand how their fate is controlled and how their regenerative potential can be harnessed. It encompasses embryonic, induced pluripotent, and adult stem cells, and addresses the molecular regulation of pluripotency, differentiation pathways, scaffold-supported culture, and translation toward therapy, alongside the ethical frameworks governing the field. The peer-reviewed research collected here reflects these themes through studies of emerging regenerative-medicine paradigms, biocompatible scaffolds for induced pluripotent stem cell transplantation and modeling post-stroke recovery in three-dimensional neural culture, and human umbilical cord-derived mesenchymal stem cells as a source of odontoblasts under good-manufacturing-practice conditions. Molecular and modeling contributions examine microRNA regulation of the pluripotency factor OCT4, estrogen receptor expression in hypothalamic stem cells, circadian oscillators in cancer stem cells, and the use of induced pluripotent stem cell-derived cardiomyocytes in compound screening and cardiotoxicity testing. The ethics of modern stem cell research and therapy situates the work within critical and interdisciplinary perspectives. Methodologically, the literature draws on cell culture, scaffold engineering, molecular biology, in vitro disease modeling, and bioethical analysis, illustrating how stem cell research connects developmental and molecular biology with biomaterials and translational medicine to advance understanding of differentiation, regeneration, and therapeutic application.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Biocompatible Scaffolds for Human-Induced Pluripotent Stem Cell Transplantation and Modeling Post-Stroke Recovery in Three-Dimensional Neural Cell Culture
Ethics of Modern Stem Cell Research and Therapy: Current Critical and Interdisciplinary Perspectives
Human Umbilical Cord-Derived Mesenchymal Stem Cells as a Source of Odontoblasts: a GMP-compliant Approach
Expression of Estrogen Receptor β in Hypothalamic Stem Cells
Therapeutic Potential of Autologous Adipose Derived Mesenchymal Stem Cells in Human POI and Ovarian Aging
MicroRNA-1285 Might Potentially Regulate OCT4 Gene Expression by Direct Targeting of its Promoter
Dual Effects of Neuroprotection and Neurotoxicity by General Anesthetics on Neural Stem Cells: Role of Autophagy
Evaluating Circadian Oscillators in Cancer Stem Cells
Osteoarthritis and Neuromuscular Deficits: Can a Causative Role be Discounted- Key 2017-2022 Observations
A Role for in Vitro Disease Models in the Landscape of Preclinical Cardiotoxicity and Safety Testing
Calcium Transient Assays for Compound Screening with Human iPSC-derived Cardiomyocytes: Evaluating New Tools
How this research is being cited
The 12 articles above have been cited 43 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2025 · Elsevier eBooks
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Taylor Anglen et al. · 2025 · bioRxiv
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2024 · Cell stem cell
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Lara G. Dresser et al. · 2024 · bioRxiv
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K. Raniga et al. · 2024 · Cell Stem Cell
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Zahirrah Begam Mohamed Rasheed et al. · 2023 · Biology
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2023 · Biology
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2023 · BMC Cancer
A sample of recent works citing this journal's research on Stem Cell Research, linking to each citing work.