Animal stem cells are undifferentiated cells of animal organisms that possess two defining properties: the capacity for self-renewal through division and the ability to differentiate into specialised cell types. They range from pluripotent cells able to form most lineages to multipotent tissue-specific cells such as…
Animal stem cells are undifferentiated cells of animal organisms that possess two defining properties: the capacity for self-renewal through division and the ability to differentiate into specialised cell types. They range from pluripotent cells able to form most lineages to multipotent tissue-specific cells such as mesenchymal and neural stem cells, and they are foundational to developmental biology, disease modelling, and regenerative medicine across human and other animal species. The studies gathered here examine stem-cell biology and its applications. Mesenchymal stem cells feature prominently, including umbilical-cord-derived cells differentiated toward odontoblasts and adipose-derived cells applied to ovarian ageing, illustrating their regenerative and therapeutic potential. Neural and pluripotent stem cells appear in work on the dual neuroprotective and neurotoxic effects of anaesthetics on neural stem cells through autophagy and on biocompatible scaffolds supporting induced pluripotent stem-cell transplantation in three-dimensional culture. Molecular regulation is addressed through the expression of estrogen receptor subtypes in hypothalamic stem cells and microRNA control of the pluripotency factor OCT4. The malignant counterpart is considered through circadian regulation in cancer stem cells, while ethical dimensions are reflected in critical perspectives on stem-cell research. Together these contributions present animal stem cells as versatile, self-renewing cells whose study underpins regenerative therapy, developmental biology, disease modelling, and the ethical frameworks guiding their use.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 41 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Animal Stem Cells, linking to each citing work.