Overview
RNA-binding proteins are a large and diverse class of proteins that recognize and associate with RNA molecules to control essentially every stage of their life cycle, including splicing, polyadenylation, transport, localization, stability, and translation. Through defined structural modules such as RNA-recognition motifs and other binding domains, they engage specific sequences or structures in their target transcripts and thereby regulate gene expression at the post-transcriptional level, a function indispensable for normal cell growth, differentiation, and stress responses. Detailed study of individual factors illustrates their biology: the RNA-binding protein RBM45, for example, has been characterized in terms of its molecular and cellular roles and analyzed for protein-domain conservation, gene architecture, and phylogenetic distribution across metazoans, revealing how such proteins are organized and have evolved. RNA-binding proteins also intersect with broader nucleic acid biology, including the synthesis and handling of nucleic acid libraries, the regulation exerted by microRNAs in disease processes such as ischaemic heart disease, and the molecular responses of cells to perturbation studied through proteomic approaches. Because their dysfunction can disrupt the precise control of transcript fate, RNA-binding proteins are implicated in a range of pathological states. Elucidating their binding specificities, domain structures, and regulatory networks is therefore central to understanding post-transcriptional gene regulation and its role in health and disease.
Research published in this journal
8 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Determination of the Proteomic Response to Lapatinib Treatment using a Comprehensive and Reproducible Ion-Current-Based Proteomics Strategy
The Novel Coronavirus 2019 (COVID-19): A Narrative Review
Rbm45 Phylogenetics, Protein Domain Conservation, and Gene Architecture in Clade Metazoa
Optimization and ZSPORE Analysis of Affinity Purification Coupled with Tandem Mass Spectrometry in Mammalian Cells
Template Independent Synthesis of Nucleic Acid Libraries
MicroRNA: New Era for Therapeutic Strategy in Ischaemic Heart Disease
Investigations of Molecular Evolutionary Mechanisms in Partially Sequenced Heat Shock Protein70 Homologue-Coding Gene of Olive Leaf Yellowing-Associated Virus Isolates from Tunisia
How this research is being cited
The 8 articles above have been cited 20 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · BMC Bioinformatics
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2025 · BMC Genomics
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2023 · Journal of Breast Cancer
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2023 · ChemBioChem
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2022 · ChemBioChem
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2020 · Jurnal Ilmu Administrasi Media Pengembangan Ilmu dan Praktek Administrasi
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2020 · Jurnal Ilmu Administrasi: Media Pengembangan Ilmu dan Praktek Administrasi
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2019 · Nature Ecology & Evolution
A sample of recent works citing this journal's research on Rna Binding Protein, linking to each citing work.