A gene is the fundamental physical and functional unit of heredity, a defined segment of DNA (or RNA in some viruses) that carries the information needed to synthesize a functional product, typically a protein or a non-coding RNA. Genes encompass coding exons, regulatory promoters and enhancers, and, in eukaryotes, …
A gene is the fundamental physical and functional unit of heredity, a defined segment of DNA (or RNA in some viruses) that carries the information needed to synthesize a functional product, typically a protein or a non-coding RNA. Genes encompass coding exons, regulatory promoters and enhancers, and, in eukaryotes, intervening introns; their sequences determine phenotype, while allelic variants and polymorphisms underlie heritable differences in traits and disease susceptibility. Gene-level analysis examines sequence variation, expression, mutation, and clinical association across organisms. Research in this area characterizes single-nucleotide and structural polymorphisms and their links to disease, including catalase exon variants, hepcidin (HAMP) promoter polymorphisms in anemia of chronic kidney disease, PPARα and tissue-factor variants in coronary heart disease, and vitamin D receptor BsmI and ApaI genotypes in dyslipidemia, alongside ACE insertion/deletion associations with type 2 diabetes. Further work addresses molecular evolutionary features of viral coding genes such as the SARS-CoV-2 spike glycoprotein, gene silencing through siRNA delivery, chromosomal clustering of human-mouse orthologs, gene-expression responses to viral proteins, and template-independent synthesis of nucleic acid libraries. The journal publishes peer-reviewed studies on gene structure, polymorphism, expression, and function, emphasizing molecular genetic approaches to human disease and comparative biology.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 27 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Gene, linking to each citing work.