Research Topic · Peer-Reviewed

Dna Damage Response

The DNA damage response is a network of cellular pathways that detect, signal, and repair damage to DNA molecules, maintaining genomic stability and preventing mutations that can lead to disease. Research published in DNA And RNA Research addresses multiple dimensions of this response system, including the molecular…

Curated from this journal's research 📚 9 peer-reviewed articles cited Cited 30× across the literature 🔖 ISSN 2575-7881 🗓 Reviewed July 2026

Overview

The DNA damage response is a network of cellular pathways that detect, signal, and repair damage to DNA molecules, maintaining genomic stability and preventing mutations that can lead to disease. Research published in DNA And RNA Research addresses multiple dimensions of this response system, including the molecular characterization of RNA-binding proteins involved in DNA damage signaling, structural and functional analysis of variants in BRCA1 that affect DNA repair capacity, and mechanisms by which oxidative stress causes telomere attrition despite antioxidant defenses. Published studies examine how cancer cells acquire resistance to apoptosis triggered by DNA damage, the redox properties of phytochemicals and their effects on DNA integrity, and regulatory pathways in colorectal cancer that influence genomic stability. Additional work explores defective cellular pathways in neurodegenerative conditions and hematopoietic disruption caused by DNA-damaging chemotherapy agents. The journal also features evolutionary and comparative genomic analyses examining chromosomal organization and compositional features of genes involved in maintaining genome integrity across species. Understanding DNA damage response mechanisms is essential for developing targeted cancer therapies, predicting disease susceptibility from genetic variants, and identifying interventions that preserve genomic stability during aging and environmental stress.

Research published in this journal

9 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2016

GR-RNF43 Regulation in Colorectal Cancer

Chan ChristinaCorresponding author
Cell and Molecular Biology Program, Michigan State University, 567 Wilson Road, Rm 2240A, East Lansing, Michigan 48824, USA
Exact topic Proteomics and Genomics Research Cited by 1 doi:10.14302/issn.2326-0793.jpgr-16-941
2019

Robust Sampling of Defective Pathways in Parkinson Disease

Luis Fernández-Martínez JuanCorresponding author
Group of Inverse Problems, Optimization and Machine Learning. Department of Mathematics. C/ Federico García Lorca, 18. 33007 Oviedo. University of Oviedo. Spain
Medical Informatics and Decision Making Cited by 2 doi:10.14302/issn.2641-5526.jmid-18-2529

How this research is being cited

The 9 articles above have been cited 30 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Dna Damage Response, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in DNA And RNA Research (ISSN 2575-7881).

Journal editorial board
jianhui zhang · United States Masayoshi Yamaguchi · United States Li Mao · United States

This page summarises published research for orientation; it is not medical or professional advice.