Research Topic · Peer-Reviewed

Colorectal Cancer

Colorectal cancer is a malignancy that arises in the colon or rectum, usually developing from precancerous adenomatous polyps in the intestinal lining through the progressive accumulation of genetic and molecular alterations. It is among the most commonly diagnosed cancers worldwide and a leading cause of cancer-rel…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 62× across the literature 🔖 ISSN 2574-4526 🗓 Reviewed July 2026

Overview

Colorectal cancer is a malignancy that arises in the colon or rectum, usually developing from precancerous adenomatous polyps in the intestinal lining through the progressive accumulation of genetic and molecular alterations. It is among the most commonly diagnosed cancers worldwide and a leading cause of cancer-related death, with risk shaped by age, family history, inflammatory bowel disease, diet, and lifestyle. Common manifestations include rectal bleeding, iron-deficiency anaemia, abdominal pain, and changes in bowel habits, and outcomes improve substantially with early detection through screening tools such as colonoscopy and faecal immunochemical testing. In the context of Digestive Disorders And Diagnosis, colorectal cancer is significant for its preventability through screening and polyp removal and for the molecular pathways underlying its development. Key aspects include screening strategies, carcinogenic signalling, biomarkers, and treatment response. Research published in this journal examines colon cancer detection in patients with iron deficiency, molecular regulation in colorectal cancer, population-based and company-based screening programmes, dietary and lifestyle factors, gene-expression changes such as VCAM-1, mechanisms of resistance to apoptosis, chemoprevention with anti-inflammatory drugs, and perioperative cardiac risk during cancer resection, reflecting a broad clinical, diagnostic, and mechanistic perspective on the disease.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2016

GR-RNF43 Regulation in Colorectal Cancer

Chan ChristinaCorresponding author
Cell and Molecular Biology Program, Michigan State University, 567 Wilson Road, Rm 2240A, East Lansing, Michigan 48824, USA
Exact topic Proteomics and Genomics Research Cited by 1 doi:10.14302/issn.2326-0793.jpgr-16-941

How this research is being cited

The 12 articles above have been cited 62 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Colorectal Cancer, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Digestive Disorders And Diagnosis (ISSN 2574-4526).

Journal editorial board
Jonas P. DeMuro · United States Divey Manocha · United States Beata Kasztelan-Szczerbinska · Poland

This page summarises published research for orientation; it is not medical or professional advice.