Research Topic · Peer-Reviewed

Colon

The colon, or large intestine, is the distal segment of the gastrointestinal tract extending from the cecum to the rectum, where it absorbs water and electrolytes, ferments residual carbohydrates via the resident microbiota, and forms and stores feces. Its mucosa is lined by columnar epithelium organized into crypts…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 62× across the literature 🔖 ISSN 2574-4526 🗓 Reviewed July 2026

Overview

The colon, or large intestine, is the distal segment of the gastrointestinal tract extending from the cecum to the rectum, where it absorbs water and electrolytes, ferments residual carbohydrates via the resident microbiota, and forms and stores feces. Its mucosa is lined by columnar epithelium organized into crypts of Lieberkuhn, with haustral folds shaping luminal contents; abnormalities in this architecture, including taller proximal haustral folds, have been examined as factors that may obscure lesions during colonoscopy and contribute to interval colorectal cancer. Clinically, the colon is a principal site of malignancy: colorectal carcinoma typically arises through the adenoma-carcinoma sequence, and its detection is approached through endoscopy, biopsy, and molecular techniques. Research in this area spans the prediction of colorectal neoplasia in patients presenting with iron deficiency, the use of microRNA quantification by digital PCR and microfluidic assays for stool-based diagnostic screening, the role of E-cadherin and apoptosis-regulating proteins such as PAR-4 in metastasis, and chemopreventive or anti-inflammatory effects of plant-derived extracts in chemically induced colon cancer models. Colon-targeted drug delivery, inflammatory bowel involvement, and ulcerative colitis pathology are further sub-areas. The journal publishes peer-reviewed clinical, pathological, and experimental studies addressing colonic structure, disease, and diagnosis.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2019

Capsaicin: A Potential Therapy Adjuvant for Intestinal Bowel Disease

I Alvarez-Leite JacquelineCorresponding author
Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerias, Brazil.
Exact topic Digestive Disorders And Diagnosis Cited by 11 doi:10.14302/issn.2574-4526.jddd-19-3063

How this research is being cited

The 12 articles above have been cited 62 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Colon, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Digestive Disorders And Diagnosis (ISSN 2574-4526).

Journal editorial board
Jonas P. DeMuro · United States Divey Manocha · United States Beata Kasztelan-Szczerbinska · Poland

This page summarises published research for orientation; it is not medical or professional advice.