Research Topic · Peer-Reviewed

Chronic Liver Disease

Chronic liver disease is the progressive, long-term deterioration of liver function arising from sustained injury, which drives inflammation, fibrosis, and ultimately cirrhosis with its attendant complications. Common causes include chronic viral hepatitis, alcohol-related and metabolic liver disease, and toxic inju…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 72× across the literature 🔖 ISSN 2574-4526 🗓 Reviewed July 2026

Overview

Chronic liver disease is the progressive, long-term deterioration of liver function arising from sustained injury, which drives inflammation, fibrosis, and ultimately cirrhosis with its attendant complications. Common causes include chronic viral hepatitis, alcohol-related and metabolic liver disease, and toxic injury, and the condition often advances silently before clinical decompensation. A central theme in this area is the epidemiology and clinical course of chronic liver disease, including retrospective hospital-based studies characterising its magnitude, trends, and patterns in different populations. A second strand concerns assessment and complications, including non-invasive measurement of liver stiffness and its relationship to decompensation and portal hypertension, and laboratory evaluation of associated disorders such as thrombocytopenia. A third addresses nutrition and protective factors, including vitamin D deficiency and its clinical significance in chronic liver disease, glycaemic considerations in liver-specific nutritional support, and the hepatoprotective effects of agents against oxidative and chemical injury. Related work examines liver cancer and outcomes in patients with coexisting conditions. Methodologically the field combines hospital cohorts, diagnostic studies, and experimental hepatoprotection models. By characterising the causes, progression, complications, and modifiable factors of chronic liver disease, research in this area informs earlier detection, risk stratification, and management aimed at slowing progression and improving outcomes.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2013

Kynurenines and Vitamin B6: Link Between Diabetes and Depression.

Oxenkrug GregoryCorresponding author
Psychiatry and Inflammation Program, Department of Psychiatry, Tufts University School of Medicine and Tufts Medical Center, Boston MA, USA.
Exact topic Bioinformatics And Diabetes Cited by 31 doi:10.14302/issn.2374-9431.jbd-13-218

How this research is being cited

The 12 articles above have been cited 72 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Chronic Liver Disease, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Digestive Disorders And Diagnosis (ISSN 2574-4526).

Journal editorial board
Jonas P. DeMuro · United States Divey Manocha · United States Beata Kasztelan-Szczerbinska · Poland

This page summarises published research for orientation; it is not medical or professional advice.