Overview
Subcutaneous tissue, also called the hypodermis or superficial fascia, is the deepest layer of the skin, lying beneath the epidermis and dermis. It is composed predominantly of lobules of adipocytes (subcutaneous fat) separated by fibrous septa of connective tissue, together with collagen and elastin fibres, blood vessels, lymphatics, and cutaneous nerves. Functionally it provides thermal insulation, mechanical cushioning and shock absorption, energy storage in the form of triglycerides, and anchorage of the overlying skin to deeper structures such as muscle and bone. The adipose component is also metabolically and endocrinologically active, secreting adipokines that participate in energy homeostasis and inflammation, which links subcutaneous fat biology to obesity and metabolic disease. Clinically, the hypodermis is the site of subcutaneous injection, the plane affected in panniculitis and cellulite, and a route through which infection can spread, as in cellulitis and surgical site infection. Disorders of adnexal and soft-tissue structures embedded within or adjacent to this layer, including sweat-gland and perineural neoplasms, also fall within its anatomical scope. The journal publishes peer-reviewed dermatologic and related research addressing the structure, physiology, pathology, and clinical management of subcutaneous and adipose tissue and the cutaneous conditions arising within it.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Understanding the Physiology of Adipose Tissue: A Key to Combat Obesity?
The Neoplastic Whorls-Soft Tissue Perineurioma
Does a Controlled Diet Improve Cellulite?
Transmutation of Sweat Glands - Eccrine Porocarcinoma
Surgical Site Infection in Cesarean Section Operation: Risk and Management
Docosahexaenoic Acid Supplementation is Not Anti- Inflammatory in Adipose Tissue of Healthy Obese Postmenopausal Women
The Mullerian Reconnaissance - Cutaneous Ciliated Cyst
Coolifting® CoolCell®, A New Group of Highly Effective Active Ingredients for the Reduction of Cellulite in Women
Reversal of Obesity: The Quest for the Optimum Dietary Regimen
Branching Pattern of the Medial Calcaneal Neurovascular Bundle in Porta Pedis of the Human Foot
A New Model of Body Composition: Concept and Design Features of the DBA-Model
How this research is being cited
The 12 articles above have been cited 49 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2025 · RCMOS - Revista Científica Multidisciplinar O Saber
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2025 · RCMOS - Revista Científica Multidisciplinar O Saber
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2025 · Genij Ortopedii
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2024 · International Journal of Molecular Sciences
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2024 · Prostaglandins, Leukotrienes and Essential Fatty Acids
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2024 · Progress in Lipid Research
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2024 · Progress in Lipid Research
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2024 · International Journal of Molecular Sciences
A sample of recent works citing this journal's research on Subcutaneous Tissue, linking to each citing work.