Overview
A skin lesion is any localized area of skin that differs from the surrounding tissue in color, texture, elevation, or structure, representing a visible or palpable change that signals an underlying process. Lesions are described by a standardized morphological vocabulary that guides diagnosis: primary lesions include macules and patches, papules, plaques, nodules, vesicles, bullae, and pustules, while secondary lesions such as scale, crust, erosion, ulceration, and scarring arise through evolution or external factors. Causes are diverse, spanning trauma, bacterial, fungal, viral, and parasitic infection, allergic and inflammatory reactions, autoimmune disease, vascular and metabolic disorders, and benign and malignant neoplasms, including actinic keratosis, basal cell carcinoma, and melanoma. Careful characterization of a lesion's size, shape, color, border, surface, distribution, and change over time, often aided by dermoscopy and confirmed by biopsy and histopathology, is central to distinguishing benign from premalignant and malignant processes. Accurate identification and monitoring underpin early detection of skin cancer and timely treatment of infections and inflammatory dermatoses. Management depends on the diagnosis and may involve topical or systemic therapy, cryotherapy, laser-based and microporation techniques, curettage, or excision. As the fundamental unit of clinical dermatology, the skin lesion translates pathological change into observable signs and anchors the assessment, diagnosis, and treatment of skin disease.
Research published in this journal
6 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The Beneficial Effect of Two Nutraceuticals in Flea Allergy Dermatitis Itch Control: A Comparative Study
The Combination of Fractionated Erbium:YAG Laser Skin Microporation and Topical Imiquimod Is A New, Safe And Efficient Strategy for the Treatment of Actinic Keratosis and Basal Cell Carcinoma: Report of Two Pilot Studies
Evaluation of Immunomodulatory Effect of a Novel Test Formulation in D-Galactose-Induced Aging Dysfunction in Sprague Dawley Rats
Advanced Virological And Clinicopathological Studies On Cattle Suffering From Foot And Mouth Disease Virus
How this research is being cited
The 6 articles above have been cited 20 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · Discover Viruses
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2025 · Elsevier eBooks
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2025 · Veterinary Immunology and Immunopathology
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Emad Abdel-Hamied et al. · 2025 · Veterinary Immunology and Immunopathology
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2022 · International Journal of Clinical Pediatric Dentistry
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2022 · International Journal of Clinical Pediatric Dentistry
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2022 · Pakistan Journal of Science
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2022 · Lasers in Surgery and Medicine
A sample of recent works citing this journal's research on Skin Lesion, linking to each citing work.