Research Topic · Peer-Reviewed

Adverse Events

An adverse event is any untoward medical occurrence in a patient or trial participant that arises during treatment or the use of a medical product, irrespective of whether a causal relationship with that treatment has been established. In clinical research and pharmacovigilance, adverse events are graded by severity…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 13× across the literature 🗓 Reviewed July 2026

Overview

An adverse event is any untoward medical occurrence in a patient or trial participant that arises during treatment or the use of a medical product, irrespective of whether a causal relationship with that treatment has been established. In clinical research and pharmacovigilance, adverse events are graded by severity and seriousness—serious adverse events being those resulting in Death, hospitalization, persistent disability, or life-threatening outcomes—and are distinguished from adverse drug reactions, in which causality is implicated. Surgical and procedural complications, medication errors, and treatment-emergent toxicities all fall within this construct. Systematic collection and analysis of adverse events underpins drug and device safety evaluation, risk-benefit assessment, and clinical risk management, and informs predictive modeling of postoperative morbidity and mortality. Reliable ascertainment depends on standardized reporting, datasets such as surgical quality registries, and rigorous trial monitoring. Research relevant to this area examines the efficacy and safety profiles of pharmacologic combinations, predictors of adverse events after major surgery drawn from national surgical datasets, postoperative biomarkers predicting cardiac morbidity and mortality, controlled-trial safety endpoints, and patient safety and clinical risk management. This peer-reviewed literature reflects the methodological and clinical dimensions of detecting, classifying, and preventing adverse events, situating treatment-related harm and mortality within the broader study of safety and outcomes.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 13 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Adverse Events, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Death.

Journal editorial board
Antonella Muscella · Italy Carole Ramsey · Australia

This page summarises published research for orientation; it is not medical or professional advice.