Colorectal cancer treatment encompasses the therapeutic strategies used to manage malignancy of the colon and rectum, selected according to tumor stage, location, molecular features, and patient condition. The principal modalities are surgical resection of the primary tumor, chemotherapy, radiotherapy, and targeted …
Colorectal cancer treatment encompasses the therapeutic strategies used to manage malignancy of the colon and rectum, selected according to tumor stage, location, molecular features, and patient condition. The principal modalities are surgical resection of the primary tumor, chemotherapy, radiotherapy, and targeted and biological agents, frequently combined in multimodal regimens and supported by attention to prevention, survivorship, and quality of life. Research relevant to treatment spans the full continuum of care. Surgical studies address resection and perioperative risk prediction, including biomarkers of cardiac morbidity in patients undergoing operation, while work on chemoprevention examines the role of nonsteroidal anti-inflammatory drugs in reducing colorectal cancer risk. Molecular investigations explore mechanisms relevant to therapy, such as the suppression of metastasis through restoration of cell-adhesion proteins, and diagnostic advances including microRNA-based detection that inform treatment decisions. Studies of carcinogenesis and serrated lesions clarify the disease processes that treatment must address, and screening and surveillance, including fecal immunochemical testing and colonoscopy, underpin earlier and more effective intervention. The psychosocial dimension is reflected in research on mental health among colorectal cancer survivors and the influence of individual, family, and community factors. Collectively this literature presents treatment as an integrated effort combining surgery, systemic therapy, prevention, and supportive care.
11 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 11 articles above have been cited 40 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Colorectal Cancer Treatment, linking to each citing work.