Colorectal cancer screening is the systematic testing of asymptomatic individuals to detect colorectal cancer and its precursor lesions at an early, more treatable stage, with the dual goals of reducing incidence through removal of premalignant polyps and lowering mortality through earlier diagnosis. Established mod…
Colorectal cancer screening is the systematic testing of asymptomatic individuals to detect colorectal cancer and its precursor lesions at an early, more treatable stage, with the dual goals of reducing incidence through removal of premalignant polyps and lowering mortality through earlier diagnosis. Established modalities include stool-based tests such as the fecal immunochemical test, endoscopic examinations including colonoscopy and sigmoidoscopy, and structured population programs that determine eligibility, intervals, and follow-up. Research in this area examines both the performance of screening tests and the design and implementation of screening programs. Studies of company-based and population-based screening evaluate compliance and yield using fecal immunochemical testing across large cohorts, and consider how programs can be developed in varied health-system settings. Investigations of proximal colonic anatomy and serrated lesions address the biological basis of interval cancers that escape detection, while work on emerging molecular approaches, including microRNA quantification in stool, points toward complementary screening tools. Behavioral and psychological dimensions, such as the experience and perceived risks of colonoscopy, are also studied alongside chemoprevention and the pathways of colorectal carcinogenesis. Together this literature treats screening as a multi-component strategy combining test accuracy, programmatic delivery, and an understanding of tumor biology to interrupt colorectal cancer before it advances.
11 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 11 articles above have been cited 36 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Colorectal Cancer Screening, linking to each citing work.