HIV treatment guidelines are evidence-based recommendations that standardise the clinical management of HIV infection, specifying when to start antiretroviral therapy, which drug regimens to use, how to monitor response, and how to manage toxicity, resistance, and co-existing conditions. They are periodically revise…
HIV treatment guidelines are evidence-based recommendations that standardise the clinical management of HIV infection, specifying when to start antiretroviral therapy, which drug regimens to use, how to monitor response, and how to manage toxicity, resistance, and co-existing conditions. They are periodically revised as new agents, trial data, and resistance patterns emerge. Research informing and applying these guidelines examines patterns of highly active antiretroviral therapy use and associated adverse drug reactions, the implementation of routine viral load monitoring and quality data systems, and the management of drug resistance in children and adolescents. Studies also address adherence, disclosure of serostatus, long-term outcomes in people on antiretroviral therapy, cardiovascular and other comorbidities, and the integration of pre-exposure prophylaxis screening into primary care. Effective guideline implementation depends not only on drug selection but on health-system factors such as laboratory capacity, provider knowledge, patient linkage and retention, and the social context of care. Across resource-varied settings, evidence highlights gaps between recommended and actual practice. As a clinical framework, HIV treatment guidelines aim to achieve durable viral suppression, prevent transmission, preserve future treatment options, and reduce morbidity and mortality, while adapting to local epidemiology, available resources, and the needs of specific populations.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 43 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on HIV Treatment Guidelines, linking to each citing work.