Antiviral therapy is the use of pharmacological agents to inhibit the replication of viruses and to limit the clinical consequences of viral infection. Unlike antibacterial drugs, antivirals must act selectively against pathogens that hijack host cellular machinery, so their targets are typically virus-specific step…
Antiviral therapy is the use of pharmacological agents to inhibit the replication of viruses and to limit the clinical consequences of viral infection. Unlike antibacterial drugs, antivirals must act selectively against pathogens that hijack host cellular machinery, so their targets are typically virus-specific steps in the replication cycle: entry and fusion, genome replication by viral polymerases, reverse transcription, integration, protein processing by viral proteases, and release of progeny virions. Drug classes include nucleoside and non-nucleoside reverse-transcriptase inhibitors, protease inhibitors, integrase inhibitors, and entry inhibitors, frequently combined in multi-target regimens to suppress replication durably and reduce the emergence of resistance. The literature gathered here reflects the breadth of antiviral and immunologically directed management. Work on HIV addresses dual-target combination strategies and adjunctive interventions intended to support immune control in seropositive individuals. Several contributions concern the response to emerging respiratory viruses, including the use of immune modulators such as interferon-gamma against pandemic infection and the clinical and radiological characterisation of viral pneumonia. Others describe herpesvirus-related disease, such as cytomegalovirus esophagitis and post-transplant lymphoproliferative disorder, in immunocompromised hosts. Together this body of work situates antiviral therapy within a wider effort to interrupt viral pathogenesis through direct-acting agents and complementary immune-based approaches.
9 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 9 articles above have been cited 14 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Antiviral Therapy, linking to each citing work.