Overview
Antiretroviral treatment (ART) is the use of combinations of medications that suppress replication of the human immunodeficiency virus (HIV), reducing viral load to undetectable levels, preserving immune function and lowering the risk of onward transmission. By targeting different stages of the viral life cycle, drug classes such as nucleoside and nucleotide reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors, protease inhibitors and integrase inhibitors are combined to maximise efficacy and limit the emergence of resistance. The advent of effective combination ART transformed HIV from a generally fatal infection into a manageable chronic condition and has been credited with substantial reductions in HIV-related morbidity and mortality. Sustained benefit depends critically on adherence, access to care, monitoring and management of drug toxicity and long-term complications. Research published in this journal addresses many of these dimensions, including the psychosocial factors that influence treatment adherence, disclosure of HIV status to children receiving therapy, patterns of use of highly active antiretroviral regimens and associated adverse drug reactions, and how adherence should be measured in resource-limited settings. Further studies consider cardiovascular and ageing-related effects in people on long-term therapy and outcomes among cohorts living with HIV, reflecting ongoing attention to the effectiveness, safety, adherence and broader clinical consequences of antiretroviral therapy.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Prevalence and Factors Associated with Disclosure of HIV Diagnosis to Infected Children Receiving Antiretroviral Treatment in Public Health Care Facilities in Gauteng, South Africa
Clinical and Immunological Beneficial Effects of Phyto V7 Consumption by HIV-1 Seropositive Individuals
High Rate of Asymptomatic Myocardial Ischemia in HIV Infected Population in Bobo-Dioulasso in Burkina Faso
Nucleoside and Nucleotide Reverse Transcriptase Inhibitors Induce Aging by Inhibiting Telomerase Function
Disability and Health Outcomes – From a Cohort of People on Long Term ART
Pattern of Use of Highly Active Antiretroviral Therapy Regimens and Pattern of Occurrence of Adverse Drug Reactions in an Indian Human Immunodeficiency Virus Positive Patients
When and How Should we be Measuring Adherence to Antiretroviral Therapy in Resource-Limited Settings?
Review of Useful Theories for Working with People Who are Living with HIV and AIDS
Correlation of Cryptococcal Antigen Assay with C-reactive Protein as Serum and Urine Biomarker in Cryptococcal Meningitis: Experience in a Tertiary Hospital
Determinants of Consistent Condom Use among HIV-Positive Women in Abia State, South-East Nigeria.
Cardiovascular Risk Factors Among People Being Treated for HIV in Nepal: A Cross-Sectional Study
How this research is being cited
The 12 articles above have been cited 51 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
-
2025 · Virology Journal
-
2024 · Scientific Reports
-
Doreen Kamori et al. · 2024 · PLoS ONE
-
2024 · PLoS ONE
-
2024 · Scientific Reports
-
Wondmneh Yoseph et al. · 2024 · International Archives of Nursing and Health Care
-
2023 · International Journal of Health Promotion and Education
-
Ivo Nchendia Azia et al. · 2023 · BMC Public Health
A sample of recent works citing this journal's research on Antiretroviral Treatment, linking to each citing work.