Research Topic · Peer-Reviewed

Circulating Tumor DNA

Circulating tumor DNA (ctDNA) is fragmented DNA shed by tumor cells into the bloodstream, where it mixes with the broader pool of cell-free DNA. Because it carries the genetic and epigenetic alterations of the tumor from which it originates, ctDNA can be analyzed through a minimally invasive blood test, often called…

Curated from this journal's research 📚 3 peer-reviewed articles cited Cited 5× across the literature 🔖 ISSN 2572-3030 🗓 Reviewed July 2026

Overview

Circulating tumor DNA (ctDNA) is fragmented DNA shed by tumor cells into the bloodstream, where it mixes with the broader pool of cell-free DNA. Because it carries the genetic and epigenetic alterations of the tumor from which it originates, ctDNA can be analyzed through a minimally invasive blood test, often called a liquid biopsy, to gain insight into a cancer's molecular characteristics. It is studied as a biomarker for detecting cancer, characterizing tumor mutations, monitoring response to treatment, tracking the emergence of resistance, and detecting residual or recurrent disease, offering a real-time and repeatable window into tumor biology without the need for tissue sampling. Within this journal's focus on Cancer Genetics And Biomarkers, related research examines circulating molecular markers in the blood of cancer patients, including a study showing that dynamic microRNA expression in the plasma of melanoma patients correlates with disease progression, PD-L1 status, and overall survival, and work on immunoassays and emerging immunogenomic approaches for immunomonitoring in cancer. Such studies reflect the broader effort to use blood-based molecular signals for non-invasive cancer detection and monitoring. This page gathers peer-reviewed, open-access research relevant to the topic.

Research published in this journal

3 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 3 articles above have been cited 5 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Circulating Tumor DNA, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Cancer Genetics And Biomarkers (ISSN 2572-3030).

Journal editorial board
Dr. Charlie Gourley · United Kingdom Dr. Xinyu Chen · United States Dr. Guru Prasad Maiti · United States

This page summarises published research for orientation; it is not medical or professional advice.