Journal of Breast Cancer Survival

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Breast Cancer Survival-Breast cancer research Bioassay-guided isolation of natural metabolites Semisynthesis of natural products Molecular modeling and drug design -Hassan Ebrahim

United States

University of Louisiana at Monroe

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Hassan Ebrahim

Address:

1800 Bienville drive,
Monroe,
Louisiana-71201,
USA.

Research Interests:

Breast cancer research Bioassay-guided isolation of natural metabolites Semisynthesis of natural products Molecular modeling and drug design

Biography:

Publications:

  1. V.A. Eterovic , M. Carrasco , D. Perez , H.Y. Ebrahim , P.A. Ferchmin , K.A. El Sayed. Cembranoids structure–activity relationship for protection against diisopropylfluorophosphate damage. Biochem. Pharmacol. 2015,97(4),627.
  2. PEGylated γ-tocotrienol isomer of vitamin E: Synthesis, characterization, in vitro cytotoxicity, and oral bioavailability. Abu-Fayyad A, Behery F, Sallam AA, Alqahtani S, Ebrahim H, El Sayed KA, Kaddoumi A, Sylvester PW, Carroll JL, Cardelli JA, Nazzal S. Eur J Pharm Biopharm. 2015 Oct;96:185-95. doi: 10.1016/j.ejpb.2015.07.022. Epub 2015 Jul 30.
  3. Araguspongine C induces autophagic death in breast cancer cells through suppression of c-Met and HER2 receptor tyrosine kinase signaling. Akl MR1, Ayoub NM, Ebrahim HY, Mohyeldin MM, Orabi KY, Foudah AI, El Sayed KA. Mar Drugs. 2015 Jan 8;13(1):288-311. doi: 10.3390/md13010288.
  4. Discovery, optimization, and pharmacophore modeling of oleanolic acid and analogues as breast cancer cell migration and invasion inhibitors through targeting Brk/Paxillin/Rac1 axis. Elsayed HE, Akl MR, Ebrahim HY, Sallam AA, Haggag EG, Kamal AM, El Sayed KA. Chem Biol Drug Des. 2015 Feb;85(2):231-43. doi: 10.1111/cbdd.12380. Epub 2014 Jul 16.
  5. The marine-derived sipholenol A-4-O-3',4'-dichlorobenzoate inhibits breast cancer growth and motility in vitro and in vivo through the suppression of Brk and FAK signaling. Akl MR, Foudah AI, Ebrahim HY, Meyer SA, El Sayed KA. Mar Drugs. 2014 Apr 14;12(4):2282-304. doi: 10.3390/md12042282.
  6. 3-O-[N-(p-fluorobenzenesulfonyl)-carbamoyl]-oleanolic acid, a semisynthetic analog of oleanolic acid, induces apoptosis in breast cancer cells. Akl MR, Elsayed HE, Ebrahim HY, Haggag EG, Kamal AM, El Sayed KA. Eur J Pharmacol. 2014 Oct 5;740:209-17. doi: 10.1016/j.ejphar.2014.07.011. Epub 2014 Jul 18.