Research Topic · Peer-Reviewed

Cell Apoptosis

Apoptosis is a regulated, energy-dependent form of programmed cell death by which multicellular organisms eliminate unwanted, damaged, or potentially harmful cells in a controlled manner. It is essential for normal development, tissue homeostasis, and immune regulation, and it serves as a defense against cells beari…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 41× across the literature 🔖 ISSN 2576-6694 🗓 Reviewed July 2026

Overview

Apoptosis is a regulated, energy-dependent form of programmed cell death by which multicellular organisms eliminate unwanted, damaged, or potentially harmful cells in a controlled manner. It is essential for normal development, tissue homeostasis, and immune regulation, and it serves as a defense against cells bearing dangerous mutations. Morphologically, apoptosis is characterized by cell shrinkage, chromatin condensation, nuclear fragmentation, and the formation of membrane-bound apoptotic bodies that are cleared without provoking inflammation, distinguishing it from necrosis. The process is executed through tightly coordinated signaling pathways, including an intrinsic mitochondrial pathway responsive to cellular stress and an extrinsic pathway triggered by death-receptor activation, both converging on proteolytic enzymes that dismantle the cell. Dysregulation of apoptosis has broad pathological significance: insufficient cell death contributes to tumor formation and resistance to therapy, whereas excessive death is implicated in degenerative and ischemic injury. Research in this area examines how chemical agents, oxidative stress, and metabolic conditions modulate cell survival and death, how apoptotic regulation can be exploited in cancer prevention and treatment, and how proteins governing the death program influence processes such as metastasis. Antioxidant and protective compounds are also studied for their capacity to limit damage-induced cell death. Understanding apoptosis is therefore central to developmental biology, oncology, and the design of therapies that restore appropriate control of cell survival.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2020

The Novel Coronavirus 2019 (COVID-19): A Narrative Review

Rezapour BarataliCorresponding author
Department of Public Health, Faculty of Health, Assistant Professor, PhD in Health education and promotion, Urmia University of Medical Sciences, Urmia, Iran
Exact topic International Journal of Coronaviruses Cited by 2 doi:10.14302/issn.2692-1537.ijcv-20-3373

How this research is being cited

The 12 articles above have been cited 41 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Cell Apoptosis, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Biotechnology and Biomedical Science (ISSN 2576-6694).

Journal editorial board
Professor Massoud Kaykhaii · Slovakia Dr. Rabiul Ahasan · Saudi Arabia Dr. Jun Wan · United States

This page summarises published research for orientation; it is not medical or professional advice.