Research Topic · Peer-Reviewed

Insulin Resistance

Insulin resistance is a condition in which the body's cells respond poorly to the hormone insulin, reducing their ability to take up glucose from the blood and leading to elevated blood sugar levels. It is a central feature in the development of type 2 diabetes mellitus and is closely linked to obesity, metabolic sy…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 166× across the literature 🔖 ISSN 2374-9431 🗓 Reviewed July 2026

Overview

Insulin resistance is a condition in which the body's cells respond poorly to the hormone insulin, reducing their ability to take up glucose from the blood and leading to elevated blood sugar levels. It is a central feature in the development of type 2 diabetes mellitus and is closely linked to obesity, metabolic syndrome, cardiovascular disease, and conditions such as polycystic ovary syndrome. When cells in muscle, liver, and fat tissue become less sensitive to insulin, the pancreas compensates by producing more, and over time this compensation may fail, allowing chronic hyperglycaemia to develop. Insulin resistance is strongly influenced by lifestyle factors, including diet, physical inactivity, and excess body weight, and can often be improved through nutrition, exercise, and weight management. Research in the field spans the metabolic and molecular mechanisms underlying impaired insulin signalling, surrogate indices for measuring insulin sensitivity, the role of nutrients and natural compounds, and links to related conditions. The journal publishes peer-reviewed research informed by bioinformatics and metabolic science reflecting these themes, including studies on the impact of nutrients on diabetes, metabolomics and bioinformatics in type 2 diabetes, the effect of cinnamon supplementation on insulin resistance in polycystic ovary syndrome, dietary approaches to reversing obesity, antioxidant micronutrients in metabolic syndrome, and the identification of insulin-sensitive versus insulin-resistant phenotypes.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2014

Bioinformatics of Metabolomics in Diabetes Mellitus Type 2

Ahmad Sliem HamdyCorresponding author
Biochemistry and internal Medicine*, Basic oral and medical sciences, College of dentistry, Qassim University, Saudi Arabia
Exact topic Bioinformatics And Diabetes Cited by 2 doi:10.14302/issn.2374-9431.jbd-13-212
2013

Kynurenines and Vitamin B6: Link Between Diabetes and Depression.

Oxenkrug GregoryCorresponding author
Psychiatry and Inflammation Program, Department of Psychiatry, Tufts University School of Medicine and Tufts Medical Center, Boston MA, USA.
Exact topic Bioinformatics And Diabetes Cited by 31 doi:10.14302/issn.2374-9431.jbd-13-218

How this research is being cited

The 12 articles above have been cited 166 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Insulin Resistance, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Bioinformatics And Diabetes (ISSN 2374-9431).

Journal editorial board
Wei Wang · United States Chol Hee Jung · Australia Emile Chimusa · United Kingdom

This page summarises published research for orientation; it is not medical or professional advice.