Overview
Type 1 diabetes mellitus is an autoimmune disorder in which T-cell-mediated destruction of pancreatic islet beta cells leads to absolute insulin deficiency and chronic hyperglycaemia, typically presenting in childhood or early adulthood with polyuria, polydipsia, weight loss, and risk of ketoacidosis. It requires lifelong exogenous insulin, and its pathogenesis and progression are studied through genetic susceptibility, residual beta-cell function, and associated autoimmune conditions. Distinguishing type 1 from type 2 diabetes informs management and research into preservation of endogenous insulin secretion. Research relevant to this area examines residual beta-cell function in type 1 diabetes, autoimmune polyglandular syndrome involving neuroimmunological disease, and trends in diabetes among children and adolescents in specialist paediatric clinics. Allied work addresses bioinformatics of metabolomics in diabetes mellitus type 2 as a comparative framework, polymorphisms associated with vascular risk, the diabetes-depression link via kynurenine pathways, gestational diabetes risk factors, and experimental diabetic models evaluating metabolic and oxidative-stress markers. These studies integrate endocrinology, immunology, genetics, and bioinformatics to clarify the autoimmune and metabolic basis of insulin-dependent diabetes. The journal publishes peer-reviewed research on the pathophysiology, genetics, and bioinformatics of diabetes, including its insulin-dependent form.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
L162v Polymorphism of Par-Α Gene, A603g Polymorphism of Tissue Factor Gene and Risk of Coronary Heart Disease in Russian Population
Bioinformatics of Metabolomics in Diabetes Mellitus Type 2
One-Third of Patients With Type 2 Diabetes Mellitus Do Not Have Coronary Artery Calcification
Pregnancy Outcome in Gestational Diabetes Mellitus under Treatment-Bangladesh Perspective
Trigonella Foenum Graecum Extract Benefits on Hematological, Biochemical and Male Reproductive System as a Complementary Therapy with Glimepiride in Treating Streptozotocin Induced Diabetic Rats
Kynurenines and Vitamin B6: Link Between Diabetes and Depression.
Association of Risk Factors in Gestational Diabetes Mellitus among Pregnant Mothers Attending at a Tertiary Care Hospital in Bangladesh
Rare Association Between Neuroimmunological Diseases: A Possible Autoimmune Polyglandular Syndrome Type IV
Trends of Diabetes in Children and Adolescents in Pediatric Endocrinology Clinic and Clinical Pediatric Diabetes Center at Al Baha Central Hospital in Saudi Arabia
What Do Primary Care Prediabetes Patients Need? A Baseline Assessment of Patients Engaging in A Technology-Enhanced Lifestyle Intervention.
Auricularia Polytricha (Mushroom) Regulates Testicular DNA Expression and Oxidative Stress Markers of Streptozotocin-Induced Diabetic Male Wistar Rat
How this research is being cited
The 12 articles above have been cited 96 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · Sage Open Nursing
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2025 · Journal of Genetic Engineering and Biotechnology
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T. Tofail et al. · 2025 · Egyptian Journal of Medical Human Genetics
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Asma Shaheen et al. · 2025 · Journal of Diabetology
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2025 · Pharmacological Research
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A. A. Raeef et al. · 2025 · Journal of Genetic Engineering and Biotechnology
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2025 · Regenerative Therapy
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2025 · Journal of Diabetology
A sample of recent works citing this journal's research on Diabetes Mellitus, Type 1, linking to each citing work.