Research Topic · Peer-Reviewed

Anti-Diabetic Medication

Anti-diabetic medications are pharmacological agents used to lower elevated blood glucose and maintain glycemic control in diabetes mellitus, thereby reducing the risk of acute and long-term complications. They are broadly divided into insulin and non-insulin therapies. Insulin and its analogues replace or supplemen…

Curated from this journal's research 📚 5 peer-reviewed articles cited Cited 54× across the literature 🔖 ISSN 2374-9431 🗓 Reviewed July 2026

Overview

Anti-diabetic medications are pharmacological agents used to lower elevated blood glucose and maintain glycemic control in diabetes mellitus, thereby reducing the risk of acute and long-term complications. They are broadly divided into insulin and non-insulin therapies. Insulin and its analogues replace or supplement endogenous hormone and are essential in type 1 diabetes and used in advanced type 2 disease. Non-insulin agents act through distinct mechanisms: some enhance insulin secretion from pancreatic beta cells, others improve insulin sensitivity in liver and peripheral tissues, reduce hepatic glucose output, slow intestinal carbohydrate absorption, or increase urinary glucose excretion, while incretin-based therapies augment glucose-dependent insulin release and suppress inappropriate glucagon secretion. Selection of therapy is individualized according to the type and severity of diabetes, the degree of residual beta-cell function, comorbidities, and the risk of adverse effects such as hypoglycemia or weight change, and combination regimens are common as the disease progresses. Beyond glucose lowering, evaluation of these medications considers their effects on metabolic, hematological, and broader physiological parameters, their use alongside nutritional and lifestyle measures, and complementary or plant-derived adjuncts studied in experimental models. The field also draws on bioinformatics and metabolomics to understand drug action and the metabolic perturbations of diabetes. Effective use of anti-diabetic medications requires balancing efficacy, safety, and patient self-management.

Research published in this journal

5 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2013

Kynurenines and Vitamin B6: Link Between Diabetes and Depression.

Oxenkrug GregoryCorresponding author
Psychiatry and Inflammation Program, Department of Psychiatry, Tufts University School of Medicine and Tufts Medical Center, Boston MA, USA.
Bioinformatics And Diabetes Cited by 31 doi:10.14302/issn.2374-9431.jbd-13-218
2014

Bioinformatics of Metabolomics in Diabetes Mellitus Type 2

Ahmad Sliem HamdyCorresponding author
Biochemistry and internal Medicine*, Basic oral and medical sciences, College of dentistry, Qassim University, Saudi Arabia
Bioinformatics And Diabetes Cited by 2 doi:10.14302/issn.2374-9431.jbd-13-212

How this research is being cited

The 5 articles above have been cited 54 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Anti-Diabetic Medication, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Bioinformatics And Diabetes (ISSN 2374-9431).

Journal editorial board
Wei Wang · United States Chol Hee Jung · Australia Emile Chimusa · United Kingdom

This page summarises published research for orientation; it is not medical or professional advice.