Research Topic · Peer-Reviewed

Alzheimer

Alzheimer's disease is a progressive neurodegenerative disorder and the most common cause of dementia, characterised by deterioration of memory, thinking, and behaviour. Its neuropathology features extracellular amyloid-beta plaques, intracellular neurofibrillary tangles of hyperphosphorylated tau, synaptic and neur…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 33× across the literature 🔖 ISSN 2998-4211 🗓 Reviewed July 2026

Overview

Alzheimer's disease is a progressive neurodegenerative disorder and the most common cause of dementia, characterised by deterioration of memory, thinking, and behaviour. Its neuropathology features extracellular amyloid-beta plaques, intracellular neurofibrillary tangles of hyperphosphorylated tau, synaptic and neuronal loss, and regional atrophy, with risk shaped by genetic, vascular, and lifestyle factors. Diagnosis combines cognitive assessment with imaging and emerging biomarkers, while current treatment is largely symptomatic, motivating research into earlier detection, novel therapeutic targets, and non-pharmacological care. The research collected here reflects this scope through studies of early prediction using optical coherence tomography imaging, knowledge gaps and misconceptions among caregivers, vagus nerve stimulation as a potential treatment, assistive technology and cognitive-behavioural programmes for adaptive skills, circular RNAs in Alzheimer's disease, the relationship between cortisol, depression, and medial temporal lobe atrophy in mild cognitive impairment, and non-pharmacological interventions for disrupted sleep in dementia. Further work addresses aggression and agitation in dementia and the contribution of genetics and epigenetics. Together they span detection, molecular mechanisms, therapy, caregiving, and behavioural management. The journal publishes peer-reviewed research on the mechanisms, diagnosis, treatment, and care of Alzheimer's disease and related dementias.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2017

JALR. New Journal, Old questions, Fresh insights

Paganelli RobertoCorresponding author
Department of Medicine & Sciences of Aging, University “G. d’Annunzio” of Chieti-Pescara, Italy
Exact topic Alzheimer's Research and Therapy doi:10.14302/issn.2998-4211.jalr-17-1884
2015

Epigenetics and Nutrition

Lundstrom KennethCorresponding author
PanTherapeuitcs, Rue des Remparts 4, CH1095 Lutry, Switzerland
Exact topic International Journal of Nutrition Cited by 2 doi:10.14302/issn.2379-7835.ijn-14-603

How this research is being cited

The 12 articles above have been cited 33 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Alzheimer, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Alzheimer's Research and Therapy (ISSN 2998-4211).

Journal editorial board
Aysun Cetinyurek Yavuz · Netherlands Elvis Freeman Acquah · Australia Silvia Ingala · Denmark

This page summarises published research for orientation; it is not medical or professional advice.