Overview
Anxiety is an emotional and physiological state of apprehension, tension and heightened arousal arising in anticipation of a perceived threat, distinct from fear, which is the response to an immediate danger. In its adaptive form anxiety mobilises attention and prepares the body to respond; it becomes pathological when it is excessive, persistent or disproportionate to circumstances and impairs functioning, as in the recognised anxiety disorders. The condition has characteristic somatic features, including increased heart rate, muscle tension, restlessness and disturbed sleep, alongside cognitive features such as worry, hypervigilance and difficulty concentrating. Its neurobiology centres on limbic circuits, particularly the amygdala and its connections, on dysregulation of the hypothalamic-pituitary-adrenal axis with altered cortisol signalling, and on neurotransmitter and neuropeptide systems, including the role of cholecystokinin in provoking fear and anxiety responses. Anxiety frequently co-occurs with depression and is influenced by life-stage transitions such as menopause and by chronic stress and occupational burnout, and it carries particular relevance in older adults, in whom it interacts with cognition, physical illness and concerns including death anxiety. Management spans psychological therapies, pharmacological treatment and a range of complementary and non-pharmacological approaches aimed at reducing arousal and improving well-being.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The Effectiveness of Treating Anxiety with Reiki
Influences of Australian nursing students’ anxiety, depression, personality and family interaction on their psychological well-being and suicidal ideation
Could Painful Experience in the Neonatal Period Trigger Persistent Anxiety-Like Behavior?
Cardiovascular Disease and Depression/Anxiety, Two Complication of Menopause Status
On the Role of Cholecystokinin (CCK) in Fear and Anxiety: A Review and Research Proposal
A Triple-Blind, Placebo-Controlled Randomized Trial of the Effect of Bilateral Alternating Somatosensory Stimulation on Reducing Stress-Related Cortisol and Anxiety During and After the Trier Social Stress Test
“Prevention of Death Anxiety by Familiarity with the Concept of Death”
Aging and Positive Psychology
Osteoarthritis, COVID-19 Social Isolation-Impacts, and Counter Solutions
How this research is being cited
The 12 articles above have been cited 50 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · Journal of Humanistic Psychology
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2026 · Experimental Aging Research
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2025 · Scientific Reports
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2025 · Journal of Bodywork and Movement Therapies
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Selver Bezgin · 2024 · Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi dergisi
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2024 · Translational Psychiatry
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2024 · Oxford University Press eBooks
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2024 · Translational Psychiatry
A sample of recent works citing this journal's research on Anxiety, linking to each citing work.