Bioequivalence studies are pharmacological investigations conducted to determine whether two formulations of a drug, most commonly a generic product and its branded reference, deliver the active ingredient to the body in a comparable way. They establish equivalence in pharmacokinetic terms, comparing how the drug is…
Bioequivalence studies are pharmacological investigations conducted to determine whether two formulations of a drug, most commonly a generic product and its branded reference, deliver the active ingredient to the body in a comparable way. They establish equivalence in pharmacokinetic terms, comparing how the drug is absorbed, distributed, metabolized, and eliminated, usually by measuring blood concentrations over time and comparing parameters such as peak concentration and total exposure within accepted statistical limits. When two products are shown to be bioequivalent, they are expected to produce the same therapeutic effect and safety profile, which is the scientific basis for approving and substituting generic medicines. These studies are therefore central to drug development and regulatory decision-making. Within the journal's coverage of Advanced Pharmaceutical Science And Technology, related work includes a liquid chromatography-tandem mass spectrometry method developed to determine a drug in human plasma in support of a bioequivalence study, illustrating the sensitive analytical techniques these investigations rely on. This page gathers peer-reviewed, open-access research relevant to bioequivalence studies, supporting readers interested in pharmacokinetics, bioanalytical method development, and the evaluation of drug formulations for therapeutic equivalence.
1 peer-reviewed article, ranked by relevance. Each links to its DOI.
The 1 article above has been cited 7 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Bioequivalence Studies, linking to each citing work.